Publications

Journals

Engineering embryonic stem cells with recombinase systems.
Schnütgen F, Stewart AF, von Melchner H, Anastassiadis K
Methods Enzymol. 2006;420;100-36. PMID: 17161696 DOI: 10.1016/S0076-6879(06)20007-7
The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse.
Nord AS, Chang PJ, Conklin BR, Cox AV, Harper CA, Hicks GG, Huang CC, Johns SJ, Kawamoto M, Liu S, Meng EC, Morris JH, Rossant J, Ruiz P, Skarnes WC, Soriano P, Stanford WL, Stryke D, von Melchner H, Wurst W, Yamamura K, Young SG, Babbitt PC, Ferrin TE
Nucleic Acids Res. 2006;34;D642-8. PMID: 16381950 DOI: 10.1093/nar/gkj097
High-throughput trapping of secretory pathway genes in mouse embryonic stem cells.
De-Zolt S, Schnütgen F, Seisenberger C, Hansen J, Hollatz M, Floss T, Ruiz P, Wurst W, von Melchner H
Nucleic Acids Res. 2006;34;e25. PMID: 16478711 DOI: 10.1093/nar/gnj026
EMPReSS: standardized phenotype screens for functional annotation of the mouse genome.
Brown SD, Chambon P, de Angelis MH,
Nat Genet. 2005;37;1155. PMID: 16254554 DOI: 10.1038/ng1105-1155
Genomewide production of multipurpose alleles for the functional analysis of the mouse genome.
Schnütgen F, De-Zolt S, Van Sloun P, Hollatz M, Floss T, Hansen J, Altschmied J, Seisenberger C, Ghyselinck NB, Ruiz P, Chambon P, Wurst W, von Melchner H
Proc Natl Acad Sci U S A. 2005;102;7221-6. PMID: 15870191 DOI: 10.1073/pnas.0502273102
The European dimension for the mouse genome mutagenesis program.
Auwerx J, Avner P, Baldock R, Ballabio A, Balling R, Barbacid M, Berns A, Bradley A, Brown S, Carmeliet P, Chambon P, Cox R, Davidson D, Davies K, Duboule D, Forejt J, Granucci F, Hastie N, de Angelis MH, Jackson I, Kioussis D, Kollias G, Lathrop M, Lendahl U, Malumbres M, von Melchner H, Müller W, Partanen J, Ricciardi-Castagnoli P, Rigby P, Rosen B, Rosenthal N, Skarnes B, Stewart AF, Thornton J, Tocchini-Valentini G, Wagner E, Wahli W, Wurst W
Nat Genet. 2004;36;925-7. PMID: 15340424 DOI: 10.1038/ng0904-925
A public gene trap resource for mouse functional genomics.
Skarnes WC, von Melchner H, Wurst W, Hicks G, Nord AS, Cox T, Young SG, Ruiz P, Soriano P, Tessier-Lavigne M, Conklin BR, Stanford WL, Rossant J,
Nat Genet. 2004;36;543-4. PMID: 15167922 DOI: 10.1038/ng0604-543
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Hansen J, Floss T, Van Sloun P, Füchtbauer EM, Vauti F, Arnold HH, Schnütgen F, Wurst W, von Melchner H, Ruiz P
Proc Natl Acad Sci U S A. 2003;100;9918-22. PMID: 12904583 DOI: 10.1073/pnas.1633296100
Functional analysis of secreted and transmembrane proteins critical to mouse development.
Mitchell KJ, Pinson KI, Kelly OG, Brennan J, Zupicich J, Scherz P, Leighton PA, Goodrich LV, Lu X, Avery BJ, Tate P, Dill K, Pangilinan E, Wakenight P, Tessier-Lavigne M, Skarnes WC
Nat Genet. 2001;28;241-9. PMID: 11431694 DOI: 10.1038/90074
Gene trapping methods for the identification and functional analysis of cell surface proteins in mice.
Skarnes WC
Methods Enzymol. 2000;328;592-615. PMID: 11075368
An LDL-receptor-related protein mediates Wnt signalling in mice.
Pinson KI, Brennan J, Monkley S, Avery BJ, Skarnes WC
Nature. 2000;407;535-8. PMID: 11029008 DOI: 10.1038/35035124
Rapid sequence analysis of gene trap integrations to generate a resource of insertional mutations in mice.
Townley DJ, Avery BJ, Rosen B, Skarnes WC
Genome Res. 1997;7;293-8. PMID: 9074932
Capturing genes encoding membrane and secreted proteins important for mouse development.
Skarnes WC, Moss JE, Hurtley SM, Beddington RS
Proc Natl Acad Sci U S A. 1995;92;6592-6. PMID: 7604039
Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity.
Trivedi CM, Luo Y, Yin Z, Zhang M, Zhu W, Wang T, Floss T, Goettlicher M, Noppinger PR, Wurst W, Ferrari VA, Abrams CS, Gruber PJ, Epstein JA
Nat Med. 2007;13;324-31. PMID: 17322895 DOI: 10.1038/nm1552
A mouse for all reasons.
International Mouse Knockout Consortium, Collins FS, Rossant J, Wurst W
Cell. 2007;128;9-13. PMID: 17218247 DOI: 10.1016/j.cell.2006.12.018
A new partner for the international knockout mouse consortium.
Collins FS, Finnell RH, Rossant J, Wurst W
Cell. 2007;129;235. PMID: 17448981 DOI: 10.1016/j.cell.2007.04.007
The knockout mouse project.
Austin CP, Battey JF, Bradley A, Bucan M, Capecchi M, Collins FS, Dove WF, Duyk G, Dymecki S, Eppig JT, Grieder FB, Heintz N, Hicks G, Insel TR, Joyner A, Koller BH, Lloyd KC, Magnuson T, Moore MW, Nagy A, Pollock JD, Roses AD, Sands AT, Seed B, Skarnes WC, Snoddy J, Soriano P, Stewart DJ, Stewart F, Stillman B, Varmus H, Varticovski L, Verma IM, Vogt TF, von Melchner H, Witkowski J, Woychik RP, Wurst W, Yancopoulos GD, Young SG, Zambrowicz B
Nat Genet. 2004;36;921-4. PMID: 15340423 DOI: 10.1038/ng0904-921

Books

von Melchner H, Stewart AF. 2004. Engineering of ES cell genomes with recombinase systems. In Handbook of stem cells, ed. R Lanza, pp. 609-22: Elsevier Academic Press

 

top of the page